The Latest: McCoy leaves after aggravating hamstring injury

The Latest on the seventh week of the NFL season (all times Eastern):

3:10 p.m.

Bills running back LeSean McCoy left the game at Miami in the third quarter after aggravating left hamstring injury.

McCoy, ranked second in the NFL in rushing, had been questionable after hurting himself in practice Wednesday. He started the game but totaled only 11 yards in eight carries before departing.

- Steven Wine reporting from Miami

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2:48 p.m.

Washington Redskins cornerback Josh Norman has been ruled out for the rest of the game with a concussion and appeared to injure his left shoulder.

Norman landed hard as Marvin Jones caught a 52-yard pass for the Detroit Lions. Norman lay on the turf before walking off the field very slowly and being carted to the locker room.

Also in the game, Detroit cornerback Darius Slay was listed as questionable with hamstring injury in the second quarter. He was replaced by Johnson Bademosi.

Slay, Detroit's best player in the secondary, made a victory-sealing interception two weeks ago against Philadelphia.

- Larry Lage reporting from Detroit.

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2:15 p.m.

Dolphins receiver Jarvis Landry was flagged for unnecessary roughness for a block that injured Bills safety Aaron Williams in the second quarter.

Williams suffered a head and neck injury when Landry hit him high, leading with his shoulder. Williams remained on his back for a couple of minutes before he slowly rose and was led to the locker room.

As Williams left the field, Landry walked over to him, said something and appeared chastened. The penalty was declined because Bills instead accepted an unrelated penalty on the Dolphins.

Landry was penalized earlier in the game for unsportsmanlike conduct for taunting.

Williams missed most of last season when he underwent neck surgery following an injury that threatened his career.

-Steven Wine reporting from Miami

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2:17 p.m.

It's Fitz Magic time again for the New York Jets.

Ryan Fitzpatrick replaced an injured Geno Smith with 4:34 left in the second quarter against the Baltimore Ravens. Smith injured his right knee while taking a sack from Baltimore's Matthew Judon, was taken to the locker room and listed as out for the game after returning to the sideline in street clothes.

Smith took over as the Jets' starter in place of Fitzpatrick, who had started the first six games but had thrown an NFL-leading 11 interceptions and just five touchdowns.

Smith got New York on the board when he tossed a short pass to Quincy Enunwa, who motored down the left sideline and outran two Ravens for a 69-yard touchdown to cut the deficit to 10-7. An excited Smith ran all the way down the field to celebrate as fireworks went off.

New York also lost center Nick Mangold to an injured right ankle in the first quarter, and linebacker Bruce Carter injured a quadriceps in the second quarter.

- Dennis Waszak reporting from East Rutherford, New Jersey

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2:10 p.m.

Eagles wide receiver Josh Huff returned a kickoff 98 yards for a touchdown against the Vikings, the first time in team history they've had a kick return for a score in consecutive games.

Wendell Smallwood returned a kickoff 86 yards for a TD in last week's 27-20 loss at Washington. Huff had a 107-yard TD return as a rookie in 2014.

- Rob Maaddi reporting from Philadelphia

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1:55 p.m.

Browns quarterback Cody Kessler is out and will not return to the game against Cincinnati after suffering a concussion.

He was hit hard while throwing a shovel pass on a scramble. He was replaced by rookie Kevin Hogan from Stanford.

Kessler was 9 of 11 for 82 yards while leading Cleveland to a 10-7 lead over state rival Cincinnati.

- Joe Kay reporting from Cincinnati

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1:45 p.m.

The Tennessee Titans already have lost right guard Chance Warmack to injured reserve, and now left guard Quinton Spain has been carted off the field.

Spain went down during an incomplete pass by Marcus Mariota with 14:23 left in the second quarter. Trainers and a doctor examined his right knee, then put him on a cart to take him to the locker room. An undrafted free agent last year out of West Virginia, Spain worked his way into the starting spot at left guard late last season and kept that job this season.

He was replaced in the lineup by Brian Schwenke.

- Teresa M. Walker reporting from Nashville, Tennessee

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1:45 p.m.

Eagles cornerback Ron Brooks was carted off the field after suffering a right knee injury late while making a tackle in the first quarter. Brooks stayed down on the ground for a few minutes and appeared to be in pain while trainers worked on his leg. He was immediately ruled out.

Earlier in the quarter, Vikings safety Andrew Sendejo injured his ankle and was questionable to return.

- Rob Maaddi reporting from Philadelphia

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1:25 p.m.

The Saints scored a touchdown on their opening drive against Kansas City, the fourth consecutive game that they have done so - a first in the Drew Brees-Sean Payton era.

The Chiefs had a promising drive sputter after Alex Smith overthrew his target on back-to-back plays, and New Orleans needed 10 plays and just over 4 minutes to march 80 yards the other way.

Brees hit Brandin Cooks from 9 yards out for the touchdown.

- Dave Skretta reporting from Kansas City

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1:13 p.m.

New York Giants kick returner Dwayne Harris suffered what looked like a serious injury when returning the final punt of the first half, but he returned to field the first punt of the fourth quarter.

Harris lay still on the ground for several minutes after the injury, was immobilized and carted off the field as his teammates prayed in the game against the Los Angeles Rams.

Neither team reported any other serious injuries.

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11:35 a.m.

New York Giants wide receiver Dwayne Harris is considered questionable to return against the Los Angeles Rams after injuring his lower back during a 2-yard punt return shortly before the end of the second quarter.

Harris returned a punt on a bounce from his own 15-yard line with 7 seconds remaining, then gained only 2 yards before being tackled low by Los Angeles Rams safety Cory Littleton.

Middle linebacker Bryce Hager and running back Chase Reynolds also landed on top of Harris, who remained on the turf for several minutes before being taken off the field with the assistance of a cart.

Harris, in his second season with the Giants, entered the game having returned eight punts for 57 yards and had returned two punts for 10 yards at the time of his injury.

- Zac Boyer reporting from London.

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11:15 a.m.

Lawrence Brownlee was chosen by the New York Jets to sing the national anthem before their game against the Baltimore Ravens, but the operatic tenor faced a difficult decision.

In a statement Sunday morning, he said he found himself ''being torn in two different directions.'' As the son of a veteran, Brownlee wrote, he was honored to be given the opportunity to sing the anthem - as he has before.

''I am grateful for the fact I have far more opportunities to succeed today as a man of color than my ancestors who were alive when the anthem was written,'' he said.

He added, however, that he ''cannot ignore how protests around the national anthem have escalated as of late. My fellow Kappa Alpha Psi fraternity brother Colin Kaepernick began the movement by silently protesting the anthem in hopes that the public discourse regarding race relations, police brutality and misconduct toward people of color would change.''

Brownlee said the San Francisco quarterback's decision is ''an act of protest which I agree with and support wholeheartedly.'' The opera star said he's hopeful ''people are gradually moving toward equality in all areas,'' and asked himself whether he would sing the anthem before the game or ''stand in silent solidarity.''

''In the end, I decided to use the voice that God has given me to sing,'' Brownlee wrote, ''to sing with the conflicting emotions that pull at my heart ... the honor, the pride, the frustration, the sadness ... Colin Kaepernick's message, the hope of my ancestors, and the sacrifice of those who gave their lives protecting our flag.

''And I will keep on singing until I can no longer do so.''

- Dennis Waszak Jr. reporting from East Rutherford, New Jersey.

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9:50 a.m.

The pregame protests were muted, with only one player, the Los Angeles Rams' Robert Quinn, raising a clenched fist during the national anthem before the start of the game against the New York Giants.

But the start of the game itself proved dramatic. On the second play from scrimmage, Giants tight end Larry Donnell took an 8-yard reception for an apparent first down - only to have the ball forced loose by Lamarcus Joyner and recovered by Rams cornerback E.J. Gaines on the Giants 35.

On the ensuing Rams' possession, Tavon Austin lost a fumble that went out of bounds and Case Keenum nearly threw a pick from a tipped ball, then hit Austin up the middle for a 10-yard strike and the game's opening TD.

- Shawn Pogatchnik reporting from London.

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9:15 a.m.

The NFL's latest experiment in internationalizing the sport - taking the game to the English home of rugby, Twickenham, for the first time - got off to a stylish start with fireworks, flames and live music from English R&B star Craig David performing from his new album, ''Following My Intuition.''

Teams of camouflaged British soldiers unfurled field-covering banners honoring the Giants and Rams as the teams' cheerleaders surrounded David's stage on the 50-yard line.

Twickenham is filled to capacity in a special 75,000-seat layout. Ticket scalpers outside the stadium could be heard appealing to buy tickets from passers-by, complaining that the original allotment had sold out online within 20 minutes.

Newly signed Giants kicker Robbie Gould took the field on his own an hour before kickoff to take some practice swings. He wore No. 5, not his usual 9 during his 11 seasons with the Chicago Bears. On the Giants roster, 9 is already taken by punter Brad Wing.

- Shawn Pogatchnik reporting from London.

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8:30 a.m.

It's another early start for NFL fans as the league starts 3+ hours early from London.

The New York Giants play the Los Angeles Rams in Twickenham Stadium, the home of England's rugby team in southwest London, to begin a slate of 13 games Sunday. It's the first London NFL game not being played at the national soccer stadium, Wembley, since the league started staging regular-season contests in the British capital in 2007.

The buildup has been overshadowed by the NFL's response to new domestic-abuse allegations against Giants kicker Josh Brown, who has been placed on NFL-ordered paid leave while the league mulls whether his original one-game suspension should be toughened. Former Bears kicker Robbie Gould, signed barely 24 hours earlier, will make his Giants debut in front of a sellout 75,000-strong crowd.

Later, the league's only undefeated team, the 5-0 Minnesota Vikings, face the Eagles in Philadelphia, while the Patriots travel to Pittsburgh to face a Steelers team without the injured Ben Roethlisberger. On Sunday night, the NFC West-leading Seahawks face an improving Cardinals squad in Arizona.

Also playing Sunday: Cleveland at Cincinnati, Washington at Detroit, Oakland at Jacksonville, New Orleans at Kansas City, Buffalo at Miami, Baltimore at the New York Jets, Indianapolis at Tennessee, San Diego at Atlanta, and Tampa Bay at San Francisco.