2024 NFL Week 2 odds, lines, spreads for all 16 games

And just like that, Week 2 of the NFL season is here.

Let's check out the lines for each NFL game at DraftKings Sportsbook, as the second week of the season is upon us. 

(All times ET)

2024 NFL Week 2 Odds

THURSDAY, SEPT. 12

BUFFALO BILLS @ MIAMI DOLPHINS 

Point spread: Dolphins -1 (Dolphins favored to win by one point or more, otherwise Bills cover)
Moneyline: Dolphins -118 favorites to win (bet $10 to win $18.47 total); Bills -102 underdogs to win (bet $10 to win $19.80 total)
Total scoring Over/Under: 51 points scored by both teams combined

SUNDAY, SEPT. 15

NEW ORLEANS SAINTS @ DALLAS COWBOYS (1 p.m., FOX and FOX Sports app)

Point spread: Cowboys -6.5 (Cowboys favored to win by more than 6.5 points, otherwise Saints cover)
Moneyline: Cowboys -290 favorites to win (bet $10 to win $13.45 total); Saints +235 underdogs to win (bet $10 to win $33.50 total)
Total scoring Over/Under: 47 points scored by both teams combined

TAMPA BAY BUCCANEERS @ DETROIT LIONS (1 p.m., FOX and FOX Sports app)

Point spread: Lions -7.5 (Lions favored to win by more than 7.5 points, otherwise Buccaneers cover)
Moneyline: Lions -375 favorites to win (bet $10 to win $12.67 total); Buccaneers +295 underdogs to win (bet $10 to win $39.50 total)
Total scoring Over/Under: 51.5 points scored by both teams combined

INDIANAPOLIS COLTS @ GREEN BAY PACKERS (1 p.m., FOX and FOX Sports app)

Point spread: Colts -3 (Colts favored to win by more than 3 points, otherwise Packers cover)
Moneyline: Colts -142 favorites to win (bet $10 to win $17.04 total); Packers +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

NEW YORK JETS @ TENNESSEE TITANS (1 p.m., CBS)

Point spread: Jets -4 (Jets favored to win by more than 4 points, otherwise Titans cover)
Moneyline: Jets -185 favorites to win (bet $10 to win $15.41 total); Titans +154 underdogs to win (bet $10 to win $25.40 total)
Total scoring Over/Under: 40.5 points scored by both teams combined

SAN FRANCISCO 49ERS @ MINNESOTA VIKINGS (1 p.m., CBS)

Point spread: 49ers -4.5 (49ers favored to win by more than 4.5 points, otherwise Vikings cover)
Moneyline: 49ers -218 favorites to win (bet $10 to win $14.59 total); Vikings +180 underdogs to win (bet $10 to win $28 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

SEATTLE SEAHAWKS @ NEW ENGLAND PATRIOTS (1 p.m., FOX and FOX Sports app)

Point spread: Seahawks -3.5 (Seahawks favored to win by more than 3.5 points, otherwise Patriots cover)
Moneyline: Seahawks -170 favorites to win (bet $10 to win $15.88 total); Patriots +142 underdogs to win (bet $10 to win $24.20 total)
Total scoring Over/Under: 38 points scored by both teams combined

NEW YORK GIANTS @ WASHINGTON COMMANDERS (1 p.m., FOX and FOX Sports app)

Point spread: Commanders -1.5 (Commanders favored to win by more than 1.5 points, otherwise Giants cover)
Moneyline: Commanders -122 favorites to win (bet $10 to win $18.20 total); Giants +102 underdogs to win (bet $10 to win $20.20 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

LOS ANGELES CHARGERS @ CAROLINA PANTHERS (1 p.m., CBS)

Point spread: Chargers -5.5 (Chargers favored to win by more than 5.5 points, otherwise Panthers cover)
Moneyline: Chargers -225 favorites to win (bet $10 to win $14.44 total); Panthers +185 underdogs to win (bet $10 to win $28.50 total)
Total scoring Over/Under: 39 points scored by both teams combined

CLEVELAND BROWNS @ JACKSONVILLE JAGUARS (1 p.m., CBS)

Point spread: Jaguars -3 (Jaguars favored to win by more than 3 points, otherwise Browns cover)
Moneyline: Jaguars -175 favorites to win (bet $10 to win $15.71 total); Browns +145 underdogs to win (bet $10 to win $24.50 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

LAS VEGAS RAIDERS @ BALTIMORE RAVENS (1 p.m., CBS)

Point spread: Ravens -8.5 (Ravens favored to win by more than 8.5 points, otherwise Raiders cover)
Moneyline: Ravens -395 favorites to win (bet $10 to win $12.53 total); Raiders +310 underdogs to win (bet $10 to win $41 total)
Total scoring Over/Under: 41 points scored by both teams combined

LOS ANGELES RAMS @ ARIZONA CARDINALS (4:05 p.m., FOX and FOX Sports app)

Point spread: Rams -1 (Rams favored to win by more than 1 point, otherwise Cardinals cover)
Moneyline: Rams -112 favorites to win (bet $10 to win $18.93 total); Cardinals -108 underdogs to win (bet $10 to win $19.26 total)
Total scoring Over/Under: 48 points scored by both teams combined

PITTSBURGH STEELERS @ DENVER BRONCOS (4:25 p.m., CBS)

Point spread: Steelers -2.5 (Steelers favored to win by more than 2.5 points, otherwise Broncos cover)
Moneyline: Steelers -155 favorites to win (bet $10 to win $16.45 total); Broncos +130 underdogs to win (bet $10 to win $17.69 total)
Total scoring Over/Under: 36.5 points scored by both teams combined

CINCINNATI BENGALS @ KANSAS CITY CHIEFS (4:25 p.m., CBS)

Point spread: Chiefs -6.5 (Chiefs favored to win by more than 6.5 points, otherwise Bengals cover)
Moneyline: Chiefs -285 favorites to win (bet $10 to win $13.51 total); Bengals +230 underdogs to win (bet $10 to win $33 total)
Total scoring Over/Under: 48 points scored by both teams combined

CHICAGO BEARS @ HOUSTON TEXANS (8:20 p.m., NBC/Peacock)

Point spread: Texans -6 (Texans favored to win by more than 6 points, otherwise Bears cover)
Moneyline: Texans -245 favorites to win (bet $10 to win $14.08 total); Bears +200 underdogs to win (bet $10 to win $30 total)
Total scoring Over/Under: 45 points scored by both teams combined

MONDAY, SEPT. 16

ATLANTA FALCONS @ PHILADELPHIA EAGLES (8:15 p.m., ESPN)

Point spread: Eagles -6 (Eagles favored to win by 6 points or more, otherwise Falcons cover)
Moneyline: Eagles -265 favorites to win (bet $10 to win $13.77 total); Falcons +215 underdogs to win (bet $10 to win $31.50 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, and follow leagues, teams and players to receive a personalized newsletter daily!