Penn State vs. Washington Prediction, Odds, Picks For College Football Week 10

The Penn State Nittany Lions travel west to kick off against the Washington Huskies on Saturday in a Week 10 college football matchup on FS1.

Let’s take a look at the odds for Penn State vs. Washington at DraftKings Sportsbook as of Nov. 7.

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Moneyline

• Penn State: +114
• Washington: -135

Spread

• Penn State +2.5: -110
• Washington -2.5: -110

Over/Under

• Over 56.5: -115
• Under 56.5: -105

From FOX Sports Research: 

• Penn State ended its four-game losing streak with its 12th straight win over Purdue.
• Washington averages the fourth-most passing yards per game in the Big Ten (276.8)
• Washington has never beaten Penn State as they are 0-4 lifetime. The last time they met was in 2024 when Penn State won 35-6.

How to Watch Penn State vs. Washington 

• Date: Saturday, Nov. 7, 2026
• Time: 3:30 p.m. ET
• TV: FS1
• Stream: Watch 3 days free on FOX One, FOXSports.com, FOX Sports App
• Location: Alaska Airlines Field at Husky Stadium, Seattle, WA