2026 CFP Title Odds: Ole Miss Soars After Statement Win Over Kiffin, LSU

Week 3 of the college football season delivered another shake-up to the national championship odds, highlighted by Ole Miss spoiling Lane Kiffin’s return to Oxford.

The Rebels defeated Kiffin and LSU 32-24, earning a signature win against their former head coach. As a result, Ole Miss’ odds to win the national championship surged.

Also, despite its Week 2 loss to Texas, Ohio State got back on track against Kent State in Week 3. Was it enough to keep the Buckeyes atop the oddsboard?

Let's check out the updated odds for who will win the College Football Playoff at DraftKings Sportsbook as of Sept. 20.

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2026 CFP Championship Winner Odds

Ohio State: +520 (bet $10 to win $62 total)
Texas: +620 (bet $10 to win $72 total)
Notre Dame: +650 (bet $10 to win $75 total)
Georgia: +650 (bet $10 to win $75 total)
Miami: +850 (bet $10 to win $95 total)
Indiana: +950 (bet $10 to win $105 total)
Ole Miss: +1500 (bet $10 to win $160 total)
LSU: +1600 (bet $10 to win $170 total)
Oregon: +2200 (bet $10 to win $230 total)
Alabama: +2500 (bet $10 to win $260 total)
USC: +3100 (bet $10 to win $320 total)
Texas Tech: +3200 (bet $10 to win $330 total)

Here is what to know about this oddsboard:

Return Rebuffed: Ole Miss made the biggest move on the board, jumping from +2700 to +1500 after defeating LSU 32-24 and spoiling Lane Kiffin’s return to Oxford. Trinidad Chambliss delivered a signature performance against his former coach, throwing for 363 yards and two touchdowns. As a result, LSU's odds to win the title dropped from +1100 to +1600.

The Favorite: Ohio State remains the national title favorite at +520. The Buckeyes quickly moved past the heartbreaking loss with a dominant 59-3 win over Kent State in Week 3. Big Ten play gets underway next for OSU, with games against Illinois, Iowa and Maryland before that big Oct. 17 showdown with Indiana.