2025 CFP Title Odds: Ohio State Favored With Quarterfinals Set

Eight teams remain in the College Football Playoff.

Here’s a look at the latest 2025 CFP odds at DraftKings Sportsbook as of Dec. 21.

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CFP Championship Winner 2025-26

Ohio State: +200 (bet $10 to win $30 total)
Indiana: +320 (bet $10 to win $42 total)
Georgia: +475 (bet $10 to win $57.50 total)
Oregon: +750 (bet $10 to win $85 total)
Texas Tech: +800 (bet $10 to win $90 total)
Alabama: +1800 (bet $10 to win $190 total)
Miami: +2200 (bet $10 to win $230 total)
Ole Miss: +2500 (bet $10 to win $260 total)

Here is what to know about the CFP title oddsboard:

Opening Results: In the first CFP contest, Alabama traveled to Norman and knocked off Oklahoma 34-24, avenging a regular-season home loss to the Sooners. Oklahoma took a 17-0 lead early in the second quarter, but was outscored 34-7 the rest of the way. Next up for the Tide? No. 1 Indiana. Oregon and Ole Miss both cruised in Round 1, over James Madison and Tulane, respectively. The Ducks now face Texas Tech, and the Rebels get a rematch against Georgia, which they lost to back in October. Lastly, Miami outlasted Texas A&M, 13-10, to book a date with the defending champion Buckeyes.

The Top Spot: No. 2 OSU (12-1) opened as the favorite to win it all, and remains there entering the quarterfinals. The Buckeyes won the CFP last year, and have only suffered one loss this season — falling to No. 1 Indiana in the Big Ten Championship Game. If Ohio State wants to return to the CFP title game, it will need to defeat Miami in the quarterfinals (Dec. 31) and then overcome the winner of Ole Miss-Georgia in the semifinals (Jan. 8). On the other side of the bracket, if Indiana wants a shot at the title, it will need to beat Alabama in the quarters (Jan. 1) and the winner of Oregon-Texas Tech in the semis (Jan. 9).

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