2023 College Football Top 25 Week 4 odds, predictions, lines, TV schedule

Published Sep 19, 2023 1:45 pm ET

Week 4 of the college football season is upon us, and it promises to be jam packed.

As Chris "The Bear" Fallica pointed out, there are six ranked matchups this week — the most ranked matchups in September since 2006.

Overall, Top-25 teams will be in action across 18 games that includes the No. 14 Oregon State Beavers taking on the No. 21 Washington State Cougars at Martin Stadium on FOX and the FOX Sports App.

Additionally, Big Noon Kickoff will feature No. 16 Oklahoma Sooners traveling to Ohio to square off against the Cincinnati Bearcats, also on FOX and the FOX Sports App.

So without further ado, stay on top of the most current betting trends with our preview below.

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Week 4 Betting Lines & Game Info

Clemson Tigers vs. No. 4 Florida State Seminoles

Odds & Prediction

Spread: Seminoles (-2.5)
Moneyline: Seminoles -135, Tigers +114
Total: 56.5 points
Prediction: Clemson 30, Florida State 29

How to Watch

Game Date: Saturday, September 23
Game Time: 12:00 PM ET
TV Channel: ABC
Location: Berkeley, California

Cincinnati Bearcats vs. No. 16 Oklahoma Sooners

Odds & Prediction

Spread: Sooners (-14.5)
Moneyline: Sooners -625, Bearcats +455
Total: 60.5 points
Prediction: Cincinnati 30, Oklahoma 29

How to Watch

Game Date: Saturday, September 23
Game Time: 12:00 PM ET
TV Channel: Watch Online: FOX
Location: Cincinnati, Ohio

UConn Huskies vs. No. 18 Duke Blue Devils

Odds & Prediction

Spread: Blue Devils (-21.5)
Moneyline: Blue Devils -1450, Huskies +850
Total: 45.5 points
Prediction: Duke 30, UConn 14

How to Watch

Game Date: Saturday, September 23
Game Time: 3:30 PM ET
TV Channel: CBS Sports Network
Location: East Hartford, Connecticut

Temple Owls vs. No. 20 Miami Hurricanes

Odds & Prediction

Spread: Hurricanes (-23.5)
Moneyline: Hurricanes -2400, Owls +1200
Total: 51.5 points
Prediction: Miami (FL) 31, Temple 21

How to Watch

Game Date: Saturday, September 23
Game Time: 3:30 PM ET
TV Channel: ESPN2
Location: Philadelphia, Pennsylvania

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Joel Klatt discussed the No. 13 Alabama Crimson Tide falling out of the AP Top 10 and their problem at quarterback.

No. 13 Alabama Crimson Tide vs. No. 15 Ole Miss Rebels

Odds & Prediction

Spread: Crimson Tide (-7)
Moneyline: Crimson Tide -285, Rebels +230
Total: 57 points
Prediction: Ole Miss 28, Alabama 27

How to Watch

Game Date: Saturday, September 23
Game Time: 3:30 PM ET
TV Channel: CBS
Location: Tuscaloosa, Alabama

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No. 10 Oregon Ducks vs. No. 19 Colorado Buffaloes

Odds & Prediction

Spread: Ducks (-21)
Moneyline: Ducks -1100, Buffaloes +700
Total: 71.5 points
Prediction: Oregon 39, Colorado 30

How to Watch

Game Date: Saturday, September 23
Game Time: 3:30 PM ET
TV Channel: ABC
Location: Eugene, Oregon

No. 11 Utah Utes vs. No. 22 UCLA Bruins

Odds & Prediction

Spread: Utes (-4.5)
Moneyline: Utes -198, Bruins +164
Total: 51 points
Prediction: UCLA 23, Utah 15

How to Watch

Game Date: Saturday, September 23
Game Time: 3:30 PM ET
TV Channel: Watch Online: FOX
Location: Salt Lake City, Utah

No. 23 Tennessee Volunteers vs. UTSA Roadrunners

Odds & Prediction

Spread: Volunteers (-20.5)
Moneyline: Volunteers -1350, Roadrunners +800
Total: 57.5 points
Prediction: Tennessee 26, UTSA 22

How to Watch

Game Date: Saturday, September 23
Game Time: 4:00 PM ET
TV Channel: SEC Network
Location: Knoxville, Tennessee

No. 12 LSU Tigers vs. Arkansas Razorbacks

Odds & Prediction

Spread: Tigers (-17.5)
Moneyline: Tigers -900, Razorbacks +600
Total: 56 points
Prediction: LSU 33, Arkansas 24

How to Watch

Game Date: Saturday, September 23
Game Time: 7:00 PM ET
TV Channel: ESPN
Location: Baton Rouge, Louisiana

No. 21 Washington State Cougars vs. No. 14 Oregon State Beavers

Odds & Prediction

Spread: Beavers (-3)
Moneyline: Beavers -148, Cougars +124
Total: 56 points
Prediction: Washington State 29, Oregon State 26

How to Watch

Game Date: Saturday, September 23
Game Time: 7:00 PM ET
TV Channel: Watch Online: FOX
Location: Pullman, Washington

No. 25 Florida Gators vs. Charlotte 49ers

Odds & Prediction

Spread: Gators (-28)
Moneyline: Gators -4500, 49ers +1700
Total: 49.5 points
Prediction: Florida 32, Charlotte 19

How to Watch

Game Date: Saturday, September 23
Game Time: 7:00 PM ET
TV Channel: SEC Network+
Location: Gainesville, Florida

No. 1 Georgia Bulldogs vs. UAB Blazers

Odds & Prediction

Spread: Bulldogs (-42)
Moneyline: Bulldogs , Blazers
Total: 54 points
Prediction: Georgia 41, UAB 17

How to Watch

Game Date: Saturday, September 23
Game Time: 7:30 PM ET
TV Channel: ESPN2
Location: Athens, Georgia

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No. 9 Notre Dame Fighting Irish vs. No. 6 Ohio State Buckeyes

Odds & Prediction

Spread: Buckeyes (-3.5)
Moneyline: Buckeyes -180, Fighting Irish +150
Total: 54.5 points
Prediction: Ohio State 30, Notre Dame 24

How to Watch

Game Date: Saturday, September 23
Game Time: 7:30 PM ET
TV Channel: NBC
Location: South Bend, Indiana

Baylor Bears vs. No. 3 Texas Longhorns

Odds & Prediction

Spread: Longhorns (-15)
Moneyline: Longhorns -675, Bears +490
Total: 51.5 points
Prediction: Texas 31, Baylor 20

How to Watch

Game Date: Saturday, September 23
Game Time: 7:30 PM ET
TV Channel: ABC
Location: Waco, Texas

No. 7 Penn State Nittany Lions vs. No. 24 Iowa Hawkeyes

Odds & Prediction

Spread: Nittany Lions (-14.5)
Moneyline: Nittany Lions -650, Hawkeyes +470
Total: 40.5 points
Prediction: Penn State 27, Iowa 17

How to Watch

Game Date: Saturday, September 23
Game Time: 7:30 PM ET
TV Channel: CBS
Location: University Park, Pennsylvania

Pittsburgh Panthers vs. No. 17 North Carolina Tar Heels

Odds & Prediction

Spread: Tar Heels (-7.5)
Moneyline: Tar Heels -298, Panthers +240
Total: 50 points
Prediction: North Carolina 24, Pittsburgh 22

How to Watch

Game Date: Saturday, September 23
Game Time: 8:00 PM ET
TV Channel: ACC Network
Location: Pittsburgh, Pennsylvania

No. 8 Washington Huskies vs. California Golden Bears

Odds & Prediction

Spread: Huskies (-21)
Moneyline: Huskies -1450, Golden Bears +850
Total: 60.5 points
Prediction: Washington 31, Cal 24

How to Watch

Game Date: Saturday, September 23
Game Time: 10:30 PM ET
TV Channel: ESPN
Location: Seattle, Washington

Arizona State Sun Devils vs. No. 5 USC Trojans

Odds & Prediction

Spread: Trojans (-34)
Moneyline: Trojans , Sun Devils
Total: 62 points
Prediction: USC 36, Arizona State 20

How to Watch

Game Date: Saturday, September 23
Game Time: 10:30 PM ET
TV Channel: Watch Online: FOX
Location: Tempe, Arizona